Sandra Orsulic, PhD is a Professor in Residence of Obstetrics and Gynecology at the David Geffen School of Medicine at the University of California, Los Angeles (UCLA)

Contact: sorsulic@mednet.ucla.edu

Genetically defined mouse ovarian cancer cells

Syngeneic mouse ovarian cancer models

Human ovarian cancer expression datasets

Human ovarian cancer tissue microarrays

MOUSE MODELS

We have generated multiple syngeneic immunocompetent mouse ovarian cancer models with defined genetic alterations

BIOMARKERS

We are identifying biomarkers for ovarian cancer diagnosis, prognosis, and individualized therapies

TUMOR MICROENVIRONMENT

We study the dynamic interactions of cancer cells with cancer-associated fibroblasts and specific immune cell subsets

PRECANCER NICHE

We are defining a putative precancer niche in fallopian tubes from women with germline BRCA1 mutations